|Structural Biology of Mammalian Fertilization and ZP Domain Proteins
|Date Posted||Sunday, 14 October 2012|
|Location||Huddinge (Stockholm), Sweden|
Department of Biosciences and Nutrition & Center for Biosciences
Huddinge (Stockholm), Sweden , SE-141 83
|Job Description||The research group of Luca Jovine at Karolinska Institutet has an opening for an outstanding and highly motivated postdoctoral fellow to study protein-protein interactions that mediate mammalian egg-sperm binding at the beginning of fertilization, as well as postfertilization rearrangements of the egg coat. Structure-function studies are also ongoing on a number of related biological systems that also depend on ZP domain proteins.
For further information, see: http://jovinelab.org; Monne' et al. Nature 456:653-657 (2008); Han et al. Cell 143:404-415 (2010); Monné & Jovine Biol. Reprod. 85:661-669 (2011).
The Department of Biosciences and Nutrition has state-of-the-art equipment for protein expression, purification and in house X-ray and EM data collection; frequent access to synchrotron sites and excellent computational facilities are also available. With their close integration of academic, clinical and industrial research, KI and the Center for Biosciences offer a highly international and collaborative environment for biomedical studies.
|Qualification||The candidate must have significant experience in studying protein-protein interactions both biochemically and using X-ray crystallography and/or electron microscopy. Previous experience with polymeric systems, as well as protein expression in mammalian and/or insect cells, will be an advantage. At least one first author paper in a high quality international peer-reviewed journal, fluency in english and a strong personal drive to excel in science are essential.|
|How to Apply||Please apply via the Karolinska Institutet NetRecruiter at: https://ki.netrecruiter.se/what:job/jobID:15422/where:4/|
|Application deadline||16 December 2012|
|Supervisor/ Principal Investigator||Luca Jovine|
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