|Structural Biology of Human Hedgehog Signaling
|Date Posted||Sunday, 14 October 2012|
|Location||Huddinge (Stockholm), Sweden|
Department of Biosciences and Nutrition & Center for Biosciences
Huddinge (Stockholm), Sweden, SE-141 83
|Job Description||As part of a long-term collaboration between the laboratories of Rune Toftgård and Luca Jovine at the Department of Biosciences and Nutrition and the Center for Biosciences of Karolinska Institutet, a postdoctoral position is available on structural studies of protein-protein interactions at the core of the human Hedgehog signaling pathway.
For further information, see: http://jovinelab.org; http://ki.se/ki/jsp/polopoly.jsp?d=22596&a=84967&l=en ; Teglund & Toftgard Biochim. Biophys. Acta 1805:181-208 (2010); Briscoe & Rohatgi EMBO Rep. 13:580-583 (2012).
The Department of Biosciences and Nutrition has state-of-the-art equipment for protein expression, purification and in house X-ray and EM data collection; frequent access to synchrotron sites and excellent computational facilities are also available. With their close integration of academic, clinical and industrial research, KI and the Center for Biosciences offer a highly international and collaborative environment for biomedical studies.
|Qualification||The candidate must have significant experience in studying protein-protein interactions using both biochemical and crystallographic approaches. Previous experience with protein expression in mammalian and/or insect cells will be an advantage. Familiarity with SAXS data colection and processing will also be a plus. At least one first author paper in a high quality international peer-reviewed journal, fluency in english and a strong personal drive to excel in science are required.|
|How to Apply||Please apply via the Karolinska Institutet NetRecruiter at: https://ki.netrecruiter.se/what:job/jobID:15431/where:4/|
|Application deadline||16 December 2012|
|Supervisor/ Principal Investigator||Luca Jovine & Rune Toftgard|
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