Bacterial cytoskeleton - biochemist/molecular biologist
Date Posted Friday, 12 October 2012
Location Jouy-en-Josas (Paris), FRANCE
Institute Information INRA
UMR1319 Micalis
I.N.R.A., Domaine de Vilvert
Jouy-en-Josas Cedex, 78352
Website: http://www.micalis.fr/micalis_eng/Poles-and-teams/Pole-Biosys/FICP-Noirot/Group-3-Carballido-Lopez
Job Description A Postdoctoral position funded by an ERC Grant is available in the ‘Bacterial Cytoskeleton and Bacterial Cell Morphogenesis’ lab headed by Dr. Rut Carballido-López (http://www.micalis.fr/micalis_eng/Poles-and-teams/Pole-Biosys/FICP-Noirot/Group-3-Carballido-Lopez) for a project in Bacterial Cell Morphogenesis. How is cell shape determined in bacteria? How do bacterial cells perceive and regulate their size and shape? Our research project combines powerful genetic, biochemical, genomic and systems biology approaches available in the model bacterium Bacillus subtilis with modern high-resolution light microscopic techniques to study the dynamics and mechanistic details of the two major determinants of cell shape in bacteria: the actin-like MreB cytoskeleton and cell wall assembly.

The postdoctoral project aims to identify and characterize novel partners of the MreB cytoskeleton to provide comprehensive functional insights into MreBs function(s). Large-scale approaches that have been implemented in our lab will be pushed forward to uncover MreB-binding proteins on a proteome-scale. Interactions of interest will be confirmed biochemically, and their biological role analyzed by genetic, biochemical and modern cell biological approaches including life cell imaging and high resolution fluorescent microscopy.

We are a well-funded lab with international character that offers a dynamic and open atmosphere in which collaborations and initiative are welcomed. Our working language is English
Qualification We are looking for an enthusiastic, highly-motivated and dynamic postdoctoral fellow with a PhD in a relevant subject area and experience in molecular biology, biochemistry and/or bacterial cell biology demonstrated by peer-reviewed high quality first author research publications. The candidate should have a strong background in bacterial genetics. Experience in membrane proteins or bacterial cell wall analysis will be considered an advantage. The successful candidate is expected to work independently and pursue an integrated approach involving classical genetic, biochemistry and cell biology methodologies. Applicants interested in developing a novel research direction in the topic will be considered (!)
How to Apply Submit a single PDF document containing an informal covering letter including your motivation and research interests, your Curriculum Vitae, publication list and contact details for at least 2 references by email to Rut CARBALLIDO-LOPEZ at rut.carballido-lopez@jouy.inra.fr. **Please indicate where/how you heard of the position in the object or in the body of your email
Application deadline Applications will be reviewed as they come. Starting date is negotiable throughout 2013 and 2014
Supervisor/ Principal Investigator Rut CARBALLIDO-LOPEZ
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