|Postdoc – Super resolution imaging of transcription factor biophysics in live cells
|Date Posted||Thursday, 11 October 2012|
Husarg. 3 Box 596
The Elf lab
|Job Description||The Elf Lab performs frontier research in the fields of transcription factor regulated gene expression and super-resolution live cell imaging. We are looking for a postdoctoral fellow with skills in single molecule biophysics for a project on transcription factor binding and diffusion in living bacterial cells.
In the Elf Lab we are investigating binding and dissociation kinetics of individual binding sites in the bacterial chromosome. Questions of interest are for example how the transcription factors are distributed in the cell and how individual molecules move in the bacterial nucleoid. To address these questions we are developing super-resolution techniques for single molecule tracking, which can be used to study fast kinetics, and microfluidics and image analysis tools, to be able to monitor many individual cells over time and to change growth conditions rapidly. We are also developing new methods for protein labeling in the living cell using artificial amino acids in order to attain more photo-stabile and less perturbative labels. You will be joining an interdisciplinary team of scientists including microbiologists, physicists, engineers, and computer scientists.
|Qualification||The successful candidate has a PhD in a for the project relevant area. A strong academic background in single molecule biophysics, bio molecular engineering or super-resolution imaging is meriting.|
|How to Apply||To apply for a postdoc position in the Elf Lab, please send your CV, cover letter and references to Irmeli Barkefors (firstname.lastname@example.org).|
|Supervisor/ Principal Investigator||Johan Elf|
Contact Phone: +46 18 471 6681
Contact Email: email@example.com
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